Status:
RECRUITING
Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment
Lead Sponsor:
Stanford University
Conditions:
Postoperative Atrial Fibrillation
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Patients undergoing first time cardiac surgery will undergo rapid atrial pacing prior to initiation of cardiopulmonary bypass to screen for AF inducibility. Patients with inducible AF will be randomiz...
Detailed Description
In the operating room, as part of the open heart surgery, the surgeon will stimulate the superior right atrium section of the heart with a pacemaker for 30 seconds just prior to starting the heart and...
Eligibility Criteria
Inclusion
- Patients scheduled for first-time non-emergent open-heart surgery for coronary artery bypass graft (CABG) revascularization, valvular repair or replacement, combined CABG with valve repair or replacement, or valve sparing aortic root repair
- Normal sinus rhythm
- No documented history of atrial fibrillation
Exclusion
- Prior surgical procedures involving heart surgery and cardiopulmonary bypass
- Any prior documented history of atrial fibrillation, atrial flutter or atrial tachycardia lasting longer than 30 seconds
- Prior history of Amiodarone treatment for the management of supraventricular tachy-arrhythmias
- Patients requiring surgical treatment of atrial arrhythmias such as pulmonary vein isolation or Maze procedure.
Key Trial Info
Start Date :
March 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2050
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT03868150
Start Date
March 1 2017
End Date
December 31 2050
Last Update
November 22 2023
Active Locations (1)
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1
Stanford University
Stanford, California, United States, 94305