Status:
TERMINATED
Computerized Cognitive Training in Young Adults With Depression
Lead Sponsor:
Queens College, The City University of New York
Conditions:
Depressive Symptoms
Eligibility:
All Genders
18-29 years
Phase:
NA
Brief Summary
The purpose of the study is to examine the benefits and mechanism of action of computerized cognitive training (CCT) on mood, neuropsychological deficits, everyday functioning, and brain activity amon...
Eligibility Criteria
Inclusion
- Age 18-29.
- Current diagnosis of MDD/persistent depressive disorder or HDRS greater than or equal to 12. 3. Daily access to smartphone or tablet with internet connection for the study duration.
- 4\. Willing and able to complete MRI, mood, and neuropsychological testing. 5. IQ \> 85.
Exclusion
- Lacks English-speaking ability as determined by self-report and clinical evaluation.
- Evidence of schizophrenia, schizoaffective disorder, psychosis, bipolar I and II disorder.
- Active suicidal ideation, intent, or plan, or past attempt within 1 year.
- Severe depression (HDRS \> 30).
- Neurological disorder (epilepsy, multiple sclerosis, traumatic brain injury, clinical stroke).
- Use of medications known to have negative impact on cognition (benzodiazepines and lorazepam equivalents \> 1mg daily, narcotics, anticholinergics).
- History of alcohol or drug abuse or dependence within past year.
- Acute, severe, unstable medical illness. For cancer, acutely ill patients (including those with metastases) are excluded, but past history of successfully treated cancer does not result in exclusion.
- Regular online brain training or regular player of non-fluency verbal games, defined as doing these procedures at a frequency of twice weekly or greater during the year prior to screening.
Key Trial Info
Start Date :
October 11 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2023
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT03869463
Start Date
October 11 2019
End Date
March 31 2023
Last Update
September 25 2023
Active Locations (1)
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1
Queens College
New York, New York, United States, 11367