Status:
ACTIVE_NOT_RECRUITING
Genetic Causes and Clinical Features of Childhood Interstitial Lung Diseases in China
Lead Sponsor:
Children's Hospital of Fudan University
Conditions:
Interstitial Lung Diseases of Childhood
Genetic Testing
Eligibility:
All Genders
Up to 18 years
Brief Summary
Recruitment of a carefully characterized cohort of chILD patients, to generate a database and biobank via collecting data on chILD in China. Importantly, compatibility with ongoing United States and E...
Detailed Description
Children Interstitial lung disease (chILD) is a heterogeneous group of rare respiratory disorders of known and unknown etiologies that are mostly chronic and associated with high morbidity and mortali...
Eligibility Criteria
Inclusion
- The chILD syndrome exists when a child with DLD has had the common causes of DLD excluded as the primary diagnosis and has at least three of the following four criteria: (1) respiratory symptoms (e.g., cough, rapid and/or difficult breathing, or exercise intolerance);(2) respiratory signs (e.g., resting tachypnea, adventitious sounds, retractions, digital clubbing, failure to thrive, or respiratory fail- ure); (3) hypoxemia; and (4) diffuse abnormalities on CXR or a CT scan.
Exclusion
- These include cystic fibrosis, congenital or acquired immunodeficiency, congenital heart disease, bronchopulmonary dysplasia, pulmonary infection, primary ciliary dyskinesia presenting with newborn respiratory distress and recurrent aspiration.
Key Trial Info
Start Date :
March 25 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2025
Estimated Enrollment :
271 Patients enrolled
Trial Details
Trial ID
NCT03869515
Start Date
March 25 2019
End Date
December 30 2025
Last Update
March 7 2024
Active Locations (1)
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1
Children's hospital of Fudan University
Shanghai, Shanghai Municipality, China, 201102