Status:
COMPLETED
CPET Predicts Long-term Survival and Positive Response to CRT
Lead Sponsor:
National Institute of Cardiology, Warsaw, Poland
Conditions:
Heart Failure With Reduced Ejection Fraction
Eligibility:
All Genders
18+ years
Brief Summary
The study tested the usefulness of cardiopulmonary exercise test (CPET) in selection of potential responders to CRT.
Detailed Description
Cardiac resynchronization therapy (CRT) is an acknowledged therapy of selected patients with heart failure (HF). One of the unresolved problems is high percentage of non-responders to CRT, reaching 40...
Eligibility Criteria
Inclusion
- HF in class III or IV according to New York Heart Association (NYHA) in the course of ischemic (ICM) or non-ischemic cardiomyopathy (NICM), QRS complex duration ≥ 120ms, EF ≤35% and dilatation of the left ventricle diastolic diameter \>55mm (LVdD), according to the ESC guidelines in 2007
- HF in NYHA class II, LBBB with QRS complex duration ≥ 150 ms according to the guidelines update in 2010
- optimal pharmacotherapy of HF in the period of three months prior to the study entry.
- the expected survival of the patient \> 1 year.
Exclusion
- severe chronic obstructive pulmonary disease (FEV1 \<30%)
- inability to perform a stress test on a treadmill
Key Trial Info
Start Date :
October 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2017
Estimated Enrollment :
122 Patients enrolled
Trial Details
Trial ID
NCT03870074
Start Date
October 1 2009
End Date
October 1 2017
Last Update
March 11 2019
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