Status:
COMPLETED
Food First Approach to Stimulate Muscle Protein Synthesis in Healthy Adults
Lead Sponsor:
University of Illinois at Urbana-Champaign
Conditions:
Hypertrophy
Eligibility:
All Genders
20-35 years
Phase:
NA
Brief Summary
In a crossover design 10 young healthy adults (20-35 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise. Immediately after exercise participants will inge...
Detailed Description
On both infusion trials, participants will report to the laboratory at 0700 h after an overnight fast. Upon arrival to the lab, the participant will fill out a questionnaire and a baseline breath samp...
Eligibility Criteria
Inclusion
- Age 20-35 years
- Recreationally-active adults: ≥ 30 min of physical activity at moderate intensity ≥ 3 times per week
- English fluency
Exclusion
- Smoking
- Known allergies to fish consumption
- Vegans
- Diagnosed GI tract diseases
- Arthritic conditions
- A history of neuromuscular problems
- Diagnosed cognitive impairments
- Recent (1 year) participation in amino acid tracer studies
- Predisposition to hypertrophic scarring or keloid formation
- Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
- High blood pressure (Systolic \> 140 mm HG; Diastolic \> 90 mm HG)
- Alcohol consumption \>10 drinks per week
- Metabolic disorders (e.g., Metabolic Syndrome, diabetes, thyroid diseases)
- Consumption of thyroid, androgenic or other medications known to affect endocrine function
- Consumption of ergogenic-leves of dietary supplements that may affect muscle mass (e.g., creatine, HMB), insulin-like substances, or anabolic/catabolic pro-hormones (e.g., DHEA) within 6 weeks prior to participation
- Currently pregnant
- A suboptimal diet quality score as assessed by ASA24 dietary records
- Asthma
- Hypogonadism
- Cardiovascular disease, arrhythmias
Key Trial Info
Start Date :
March 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 22 2019
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03870165
Start Date
March 1 2019
End Date
November 22 2019
Last Update
September 28 2020
Active Locations (1)
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1
Freer Hall
Urbana, Illinois, United States, 61801