Status:
UNKNOWN
Multicenter, Prospective Study for Urinary Exosomal Biomarkers of Kidney Allograft Tubulointerstitial Fibrosis
Lead Sponsor:
Asan Medical Center
Collaborating Sponsors:
Korea University Anam Hospital
Inje University
Conditions:
Renal Fibrosis
Kidney Transplant Failure
Eligibility:
All Genders
18-70 years
Brief Summary
The investigators aim to identify urinary exosomal biomarkers that represent the extent of graft fibrosis from deceased donor kidney transplantation. Urinary samples will be collected from deceased ki...
Detailed Description
Interstitial fibrosis and tubular atrophy (IFTA), previously known as chronic allograft nephropathy (CAN), is diagnosed by pathologic changes involving all parts of the renal parenchyma and is one of ...
Eligibility Criteria
Inclusion
- end-stage renal disease patients receiving kidney transplantation from deceased donors who have the ability to provide content for this study
Exclusion
- multi-organ transplantation candidate or history of previous transplant, history of extra-renal solid organ or bone marrow or stem cell transplant, active infection, history of recent intoxication of alcohol or substance abuse within 24 weeks
Key Trial Info
Start Date :
May 11 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2022
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03870542
Start Date
May 11 2019
End Date
April 1 2022
Last Update
September 24 2019
Active Locations (1)
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1
Asan Medical Center
Seoul, South Korea, 05505