Status:
ACTIVE_NOT_RECRUITING
Dietary Oxalate and Immune Cell Function
Lead Sponsor:
University of Alabama at Birmingham
Conditions:
Kidney Stone
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate mitochondrial function in white blood cells and platelets from healthy individuals following dietary oxalate intake.
Detailed Description
Inflammation and dietary oxalate have been shown to play an important role in the development of kidney stones. Oxalate is a small molecule found in plants and plant-derived food. Individuals that hav...
Eligibility Criteria
Inclusion
- Mentally competent adults who are able to read and comprehend the consent form, written in English
- Male or Female
- Age 18 to 70 years
- Non-tobacco users
- BMI between 19 and 27
- Willingness to abstain from vigorous exercise during study period
- Normal blood comprehensive metabolic panel
Exclusion
- Mentally incompetent adults who are unable to read or comprehend the consent form, written in English
- Pregnant females
- Active medical problems
- History of kidney stones
- Any medical disorder that could influence absorption or excretion of oxalate
- BMI less than 19 or greater than 27
- Tobacco users
- Current use of medications or dietary supplements
Key Trial Info
Start Date :
July 21 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT03877276
Start Date
July 21 2016
End Date
December 1 2027
Last Update
June 9 2025
Active Locations (1)
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1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35233