Status:
TERMINATED
Alterations in Intestinal Mucosal Barrier Visualized by Confocal Laser Endomicroscopy in Liver Cirrhosis: a Pilot Trial (AMBIC)
Lead Sponsor:
Dr.med. Monica Rusticeanu
Collaborating Sponsors:
Insel Gruppe AG, University Hospital Bern
University of Bern
Conditions:
Liver Cirrhoses
Eligibility:
All Genders
18-80 years
Brief Summary
Clinical trial with medical devices. A diagnostic trial conducted to find a better (less invasive) procedure for predicting the onset of spontaneous bacterial peritonitis(SBP), which is a complication...
Eligibility Criteria
Inclusion
- Adult individual (\>18yo) with liver cirrhosis of any cause and healthy controls undergoing elective endoscopy
Exclusion
- Patients younger than \< 18, older than 80 years
- Pregnant or breastfeeding women
- Known allergy to fluorescein.
- Cardiac disease
- Asthma bronchiale
- Patients with inability or unwillingness to provide blood samples or samples of ascitic fluid.
- patients unable to give informed consent
- non-resident patients
- contraindication for an endoscopic examination
Key Trial Info
Start Date :
November 20 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 20 2019
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT03878563
Start Date
November 20 2017
End Date
June 20 2019
Last Update
July 13 2020
Active Locations (2)
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1
Limmattal Spital
Schlieren, Canton of Zurich, Switzerland, 8952
2
Universitätsspital Bern
Bern, Switzerland, 3010