Status:
UNKNOWN
Post-operative Ileus and Gut Microbiota
Lead Sponsor:
First Affiliated Hospital of Harbin Medical University
Conditions:
Post-operative Ileus
Eligibility:
All Genders
35-80 years
Brief Summary
Postoperative ileus (POI) is a common clinical condition after abdominal surgical procedure, leading to increased patient morbidity and prolonged hospitalisation.The mechanism of POI is not very clear...
Detailed Description
Postoperative ileus (POI) is a common clinical condition after abdominal surgical procedure, leading to increased patient morbidity and prolonged hospitalisation. The clinical manifestations include ...
Eligibility Criteria
Inclusion
- Requirements of informed consent and assent of participant, parent or legal guardian as applicable
- Patients with colorectal cancer scheduled for radical coloproctectomy and between the age of 35 and 80 years old without considering sex.
- Patients with BMI= 18.5-23.9
Exclusion
- Patients with colorectal cancer with distant metastasis
- Chronic renal diseases and hepatic cirrhosis
- Chronic ischemic heart disease with unstable angina, chronic heart failure at class III or IV and acute myocardial infarction in the last 6 months
- Individuals with a history of Chronic diarrhea
- Individuals with a history of Diabetes mellitus
- Individuals with a history of Hypertension
- Individuals with a history of autoimmune diseases
- Use of antibiotics and probiotics 3 mouth before samples collection
- Individuals with a history of abdominal operation due to any reason
- Individuals with any history of cancer other than colorectal cancer
- Individuals with Inflammatory bowel disease
Key Trial Info
Start Date :
April 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04009954
Start Date
April 1 2019
End Date
December 31 2020
Last Update
July 8 2019
Active Locations (1)
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1
First affiliated hospital of Harbin medical university
Harbin, Heilongjiang, China, 150001