Status:

COMPLETED

High-intensity Interval Training and Mixed Meal Responses in Persons With Spinal Cord Injury

Lead Sponsor:

University of Bath

Conditions:

Paraplegia

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Persons with chronic paraplegia at an increased risk of developing cardiovascular disease and type-2 diabetes compared to the able-bodied population. There is mounting evidence from the able-bodied li...

Detailed Description

The aim of this research is to determine the metabolic responses to a mixed-meal tolerance test following a bout of HIIT and MICT in persons with chronic paraplegia. The hypothesis is that HIIT and MI...

Eligibility Criteria

Inclusion

  • Individuals with a chronic (\>12 months post-injury) SCI below T2
  • Individuals who spend \>75% of their waking day in a wheelchair
  • Weight stable (weight not changed by \>3% over the last 3 months)

Exclusion

  • Individuals who an acute (\<12 months post-injury) SCI
  • Individuals who spend \<75% of their waking day in a wheelchair
  • Individuals on type-2 diabetes medication
  • Individuals with a peanut allergy
  • Individuals who self-report use of lipid-lowering agents
  • Individuals self-reporting active medical issues (pressure sores, urinary tract infections, cardiac disorders, musculoskeletal complaints of the upper extremities, or cardiovascular contraindications to exercise testing)
  • Individuals who report uncontrolled or regular autonomic dysreflexia

Key Trial Info

Start Date :

April 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 31 2020

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04011137

Start Date

April 1 2018

End Date

March 31 2020

Last Update

July 29 2022

Active Locations (1)

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1

Department for Health

Bath, United Kingdom, BA2 7AY