Status:
UNKNOWN
Prognosis and Integrative Assessment of Aortic Coarctation Patients in China
Lead Sponsor:
Beijing Institute of Heart, Lung and Blood Vessel Diseases
Collaborating Sponsors:
Beijing Anzhen Hospital
Bayi Children's Hospital Affiliated to PLA Army General Hospital, China
Conditions:
Coarctation of Aorta
Eligibility:
All Genders
Up to 17 years
Brief Summary
This is a systemic research of Chinese aortic coarctation patients, aiming to determine risk factors and serial biomarkers of aortic coarctation in prognosis.
Detailed Description
The goal is to determine how much the left ventricle remodeling pre-operation and how it changes in the following-up duration after surgery, so does in the blood pressure and heart function. Risk fact...
Eligibility Criteria
Inclusion
- Diagnosis of isolated coarctation of the aorta, or accompanied with atrial septal defect(ASD), ventricular septal defect (VSD), patent ductus arteriosus( PDA), patent foramen ovale (PFO);
- Patients who can cooperation with study procedures.
Exclusion
- Co-morbidities that may independently affect cardiovascular function, including associated complicated congenital heart disease, such as hypoplastic left heart syndrome (HLHS), interruption of aortic arch (IAA), Shone Syndrome, moderate and severe mitral stenosis;
- History of known vasculopathy, genetic syndromes, diabetes mellitus, hyperlipoidemia or other cardiovascular risk factors.
Key Trial Info
Start Date :
March 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04011956
Start Date
March 1 2019
End Date
December 31 2023
Last Update
July 14 2020
Active Locations (1)
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1
Beijing Anzhen Hospital
Beijing, Beijing Municipality, China, 100029