Status:
COMPLETED
Viral and Microbial Circulation Between Humans, Domesticated and Wild Animals Along an Ecotone, Democratic Republic of Congo
Lead Sponsor:
Institut Pasteur
Collaborating Sponsors:
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo
Centre National de la Recherche Scientifique, France
Conditions:
Zoonotic Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study will evaluate the overlap between the intestinal microbiome and virome of wild and domesticated animals and human beings living in close proximity in three sites along an ecotone (ecologica...
Detailed Description
The MICROTONE study sheds light on zoonotic disease emergence by examining social and ecological pathways facilitating microbial and viral flows between people and selected wild and domesticated anima...
Eligibility Criteria
Inclusion
- Age 18 years or older
- Accept participation in study
- Residing in one of three villages selected
- In good health and able to conduct habitual daily activities
- Accept self-collection of 2g of stool
- Accept blood collection (2-2.5 ml) by a medical professional
- Accept to self-collect daily activities and contacts with selected wild and domesticated animals for five months
- Accept to participate in an anthropological-historical interview on changing practices and contacts with wild and domesticated animals
Exclusion
- Vulnerable adults will not be included
- Women who are pregnant or nursing at the time of recruitment and inclusion will not be included.
- Adults declaring themselves ill and unable to conduct their habitual daily activities will not be included.
- Adults with a chronic illness will not be included
- Adults who have a family member already included in the study will not be included.
- Adults refusing either recording of interviews or note-taking during interviews will not be included.
Key Trial Info
Start Date :
March 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 21 2021
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04012164
Start Date
March 15 2019
End Date
September 21 2021
Last Update
March 27 2024
Active Locations (1)
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1
INRB
Kinshasa, Democratic Republic of the Congo