Status:
UNKNOWN
Modulation of Cognition and Brain Connectivity by Noninvasive Brain Stimulation in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease
Lead Sponsor:
Masaryk University
Collaborating Sponsors:
St. Anne's University Hospital Brno, Czech Republic
Conditions:
Mild Cognitive Impairment
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Alzheimer's disease (AD) has a detrimental impact on cognitive functions. Based on pilot studies results in patients with neurodegenerative brain diseases the investigators aim for promoting the brain...
Detailed Description
Intensified intermittent theta-burst stimulation (iTBS) protocol will be applied in the MCI study group. A two-parallel-group, randomized, placebo controlled design will be used. Ten MCI subjects will...
Eligibility Criteria
Inclusion
- amnestic single or multi-domain mild cognitive impairment patients in accordance with diagnostic criteria (Albert et al., 2011)
Exclusion
- psychiatric disorders, including major depression, major vascular lesions, and other brain pathologies detected by MRI that might present with cognitive decline
- a cardio pacemaker or any MRI-incompatible metal in the body
- epilepsy
- any diagnosed psychiatric disorder
- alcohol/drug abuse
- lack of cooperation
- presence of dementia
Key Trial Info
Start Date :
April 30 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04012346
Start Date
April 30 2018
End Date
December 1 2019
Last Update
July 9 2019
Active Locations (1)
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1
Ceitec Masaryk University
Brno, Czechia, 62500