Status:

UNKNOWN

Evaluation of C13 Breath Test for Upper Gastrointestinal Bleeding in Patients Who Need Double Antiplatelet After PCI

Lead Sponsor:

Chongqing Medical University

Conditions:

Acute Myocardial Infarction

Eligibility:

All Genders

24-93 years

Brief Summary

Hp infection is closely related to upper gastrointestinal bleeding in patients who need dual-antiplatelet after PCI. Taking anti-Hp treatment has the effect of reducing bleeding risk. Thus, we propose...

Detailed Description

Our study is to retrospectively analyze the clinical data of 1606 patients of acute myocardial infarction who need dual- antiplatelet after PCI.The diagnostic criteria for upper gastrointestinal bleed...

Eligibility Criteria

Inclusion

  • The diagnosis of patients with coronary heart disease is based on the diagnostic criteria of ACA/AHA,the diagnostic criteria for upper gastrointestinal bleeding refer to the guidelines for the diagnosis and treatment of acute non-variceal upper gastrointestinal bleeding.
  • In the hospital, all patientsI were treated with clopidogrel 300 mg or ticagrelor 180 mg before surgery, and C13 breath test was performed after surgery.
  • All patients were treated with dual- antiplatelet.
  • The clinical data of the included subjects were complete.

Exclusion

  • Patients with previous liver and kidney disease, Cr greater than 150 μmol / L, AST or ALT increased more than 2 times the normal value of patients.
  • Patient with history of cerebrovascular disease.
  • Patients with active gastrointestinal bleeding disease due to cirrhosis or other reasons before PCI.
  • Patients with abnormal coagulation.
  • Diabetic patients, diagnostic criteria for anemia: 8th edition of internal medicine, adult males with Hb less than 120g / L or RBC less than 4 × 10\^12 / L, adult women with Hb less than 105g / L or RBC than 3.5 × 10\^12 / L.
  • Patients with incomplete medical records;7.Patient with pregnant.
  • Patients with malignant tumors

Key Trial Info

Start Date :

January 1 2015

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2020

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT04012801

Start Date

January 1 2015

End Date

July 1 2020

Last Update

March 4 2020

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