Status:

COMPLETED

Effects of Escitalopram on the Sleep EEG Power in Patients With Major Depressive Disorder

Lead Sponsor:

Peking University Sixth Hospital

Collaborating Sponsors:

National Institute on Drug Dependence, China

Conditions:

Depressive Disorder, Major

Eligibility:

MALE

22-40 years

Phase:

NA

Brief Summary

The main objective was to compare the differences of PSG parameters and plasma melatonin levels before and after treatment with escitalopram for 8 weeks. Polysomnography (PSG) was detected over a nigh...

Detailed Description

1. Design and participants: The patients with MDD were screened from the hospital, age- and gender-matched healthy controls were recruited by advertising from the community who signed written informed...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of MDD;
  • Hamilton Rating Scale for Depression 17-items (HRSD-17) total scores ≥ 22;
  • Male patients aged between 18 and 45 years

Exclusion

  • Significant suicide risk by HRSD suicide scores \> 2;
  • Accompanied with psychiatric symptoms;
  • Treated with MECT within 6 months.

Key Trial Info

Start Date :

May 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2018

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT04013464

Start Date

May 1 2016

End Date

December 30 2018

Last Update

July 9 2019

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Effects of Escitalopram on the Sleep EEG Power in Patients With Major Depressive Disorder | DecenTrialz