Status:

COMPLETED

Effect of Preoperative Oral Carbohydrates on the Glycemic Variability of Diabetic Patients

Lead Sponsor:

Yonsei University

Conditions:

Diabetes

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

Preoperative carbohydrate drink intake attenuate insulin resistance. However, carbohydrate loading may compromise blood glucose control in patients with diabetes. There is some evidence that oral carb...

Eligibility Criteria

Inclusion

  • 1\. Patients undergoing total knee arthroplasty

Exclusion

  • 1\. Patients with contraindications to spinal anesthesia (local infection, clotting disorders, anatomical abnormalities, sepsis, etc.)
  • 2\. Patients with gastroesophageal reflux disease, gastric emptying disorders, inflammatory bowel disease, or previous treatment for intra-abdominal cancer
  • 3\. Patients with chronic renal disease or severe cardiovascular disease
  • 4\. HbA1c \>69 mmol/mol or BMI \>30 kg/m2
  • 5\. A duration of ≥5 hours between consumption of CHO and initiation of surgery.
  • 6\. The subject is a foreigner or illiterate

Key Trial Info

Start Date :

August 20 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 15 2020

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04013594

Start Date

August 20 2019

End Date

October 15 2020

Last Update

May 25 2021

Active Locations (1)

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Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine

Seoul, South Korea, 03722