Status:

COMPLETED

SNMC (Stronger Neo-Minophagen C ) for Acute Hepatitis Post Transarterial Chemoembolization Therapy

Lead Sponsor:

Chimei Medical Center

Conditions:

Hepatocellular Carcinoma

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

A glycyrrhizin-containing product, Stronger Neo-Minophagen C TM (SNMC; Minophagen Pharmaceutical Co.Ltd.,Tokyo,Japan),is widely used in Japan for suppression of hepatitis activity and for prevention o...

Detailed Description

Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world and the most common primary liver cancer. There are a variety of therapies for treatment of HCC; among them, transarterial c...

Eligibility Criteria

Inclusion

  • Intermediate-stage HCC according to the Barcelona Clinic Liver Cancer (BCLC) staging system, either treatment naïve or experienced.
  • Child's score belong to A or B(7)
  • Total bilirubin level \<2 and Prothrombin time prolong \<3"

Exclusion

  • Had history of liver decompensation (ascites, encephalopathy, jaundice and varices bleeding) before this TACE
  • has allergic history of SNMC
  • consensus form cannot be available
  • hypokalemia (\<3.5 mmol/L)

Key Trial Info

Start Date :

April 12 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 28 2019

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04015245

Start Date

April 12 2018

End Date

May 28 2019

Last Update

July 10 2019

Active Locations (1)

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ChiMei Medical Center

Tainan, Taiwan, 71004