Status:
COMPLETED
An Evaluation of Folic Acid to Improve Endothelial Sensitivity to Shear Stress in Seniors
Lead Sponsor:
Montreal Heart Institute
Conditions:
Healthy Aging
Aging
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate if folic acid improves endothelial sensitivity to shear stress in post-menopausal women.
Detailed Description
Cardiovascular diseases (CVD) have remained the leading cause of death globally for the last 15 years. Considering that advancing age is the primary risk factor for CVD, an increasingly aging populati...
Eligibility Criteria
Inclusion
- ≥ 1-year amenorrhea
- Body mass index ≤ 30 kg/m2
- Resting blood pressure \< 140 / \< 90 mmHg
- Non-smoker (≥ 1-year)
Exclusion
- Diagnosis of cardiac, vascular, respiratory, neurological or metabolic disease and/or a prescription of medications for the treatment of such diseases.
- For female participants, hormonal replacement therapy within 1 year of enrolment in the study.
- For female participants, having undergone an ovariectomy.
Key Trial Info
Start Date :
September 9 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 3 2024
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT04016090
Start Date
September 9 2019
End Date
April 3 2024
Last Update
December 12 2024
Active Locations (1)
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1
Cardiovascular Prevention and Rehabilitation Centre of the Montreal Heart Institute
Montreal, Quebec, Canada, H1T1N6