Status:

COMPLETED

Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

Lead Sponsor:

Florida State University

Collaborating Sponsors:

National Institute of Nursing Research (NINR)

Conditions:

Osteo Arthritis Knee

Eligibility:

All Genders

50-85 years

Phase:

NA

Brief Summary

The purpose of this study is to assess the feasibility, acceptability, and efficacy of self-administered transcranial direct current stimulation (tDCS) in older adults with knee osteoarthritis (OA)

Eligibility Criteria

Inclusion

  • have symptomatic knee OA based on American College of Rheumatology Clinical criteria
  • have had knee OA pain in the past 3 months with an average of at least 30 on a 0-100 NRS for pain
  • can speak and read English
  • have no plan to change medication regimens for pain throughout the trial

Exclusion

  • prosthetic knee replacement or nonarthroscopic surgery to the affected knee
  • history of brain surgery, brain tumor, seizure, stroke or intracranial metal implantation
  • systemic rheumatic disorders, including rheumatoid arthritis, systemic lupus erythematosus, and fibromyalgia
  • alcohol/substance abuse
  • current use of sodium channel blockers, calcium channel blockers and NMDS receptor antagonists
  • diminished cognitive function that would interfere with understanding study procedures(i.e., Mini-Mental Status Exam score ≤ 23)
  • pregnancy or lactation
  • hospitalization within the preceding year for psychiatric illness
  • no access to a device with internet access that can be used for secure videoconferencing for real-time remote supervision

Key Trial Info

Start Date :

October 18 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 5 2021

Estimated Enrollment :

123 Patients enrolled

Trial Details

Trial ID

NCT04016272

Start Date

October 18 2019

End Date

November 5 2021

Last Update

May 10 2023

Active Locations (1)

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1

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030