Status:
COMPLETED
tDCS and Glucose Uptake in Leg Muscles
Lead Sponsor:
University of Iowa
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
This study is to examine the efficacy of tDCS to improving walking in people with Multiple Sclerosis (PwMS). Our study compromises 1 group of subjects with MS which will attend the lab for three sess...
Detailed Description
Prospective participants, men and women with MS, will be recruited. The plan is to enroll up to 30 to get 20 evaluable subjects. To accomplish this study, all participants will need to complete 3 sess...
Eligibility Criteria
Inclusion
- medically diagnosed with Multiple Sclerosis (MS)
- 18-70 yrs. of age, moderate disability (Patient Determined Disease Steps (PDDS) core 2-6)
- Self-reported differences in function between legs, able to walk for 20 min.
Exclusion
- MS relapse within last 60 days
- inability to fast for 6 hours
- hyperglycemia (fasting blood sugar \> 200 mg/dL)
- insulin-dependent diabetes
- high risk for cardiovascular disease (ACSM risk classification)
- changes in disease-modifying medications within last 45 days
- concurrent neurological/neuromuscular disease
- hospitalization within last 90 days
- diagnosed depression
- inability to understand/sign informed consent, pregnant, history of seizure disorders (or on medications known to lower seizure threshold)
- hydrocephalus.
Key Trial Info
Start Date :
December 6 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2020
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT04016844
Start Date
December 6 2019
End Date
October 1 2020
Last Update
January 25 2023
Active Locations (1)
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1
University of Iowa
Iowa City, Iowa, United States, 52242