Status:
COMPLETED
The Role of Protein Tyrosine Kinase 7 (PTK7) in Non-small Cell Lung Cancer
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Tumor Progression
Eligibility:
All Genders
20-90 years
Brief Summary
To understand the mechanism and cellular functions of PTK7-associated signaling pathways in promoting lung cancer progression and conferring treatment to epidermal growth factor receptor tysosine kina...
Detailed Description
* RNA extraction: We will extract total RNA from cell lysates by using Tri-reagent (Molecular Research Center, Inc., Cincinnati, Ohio) and an RNA Mini Kit (Qiagen, Hilden, Germany) according to the ma...
Eligibility Criteria
Inclusion
- Residual specimens under the project (201103013RC: RNA based gene testing using diagnostic minute samples for personalized therapy of lung cancer) will be used in the study.
- Patients have signed the informed consent (201103013RC) before 2019/01/31 and authorized the Institutional Review Board of Nation Taiwan University Hospital to review the new study for approving the usage of residual specimens.
- The residual samples from various sources, including surgical tissues, computed tomography (CT)-guided needle aspiration and/or biopsy, echo-guided needle aspiration and /or biopsy, bronchoscopic biopsy or brushing, bronchoalveolar lavage (BAL), endobronchial ultrasound guided needle aspiration, and lymph node aspiration, and pleural effusion specimens. The samples will be collected at the time of diagnostic procedure performed. All patients should sign an informed consent for purpose of using samples for molecular genetic testing.
- 600 residual specimens will be used for the study.
Exclusion
- Patients didn't sign the informed consent (201103013RC).
- The residual specimens are not qualified.
- Patients didn't take epidermal growth factor receptor inhibitors.
Key Trial Info
Start Date :
April 19 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 24 2020
Estimated Enrollment :
167 Patients enrolled
Trial Details
Trial ID
NCT04018183
Start Date
April 19 2019
End Date
March 24 2020
Last Update
March 25 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Jin-Yuan Shih
Taipei, Taiwan