Status:
UNKNOWN
The Effects of Allogeneic SLET
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Limbal Stem-cell Deficiency
Eligibility:
All Genders
10-90 years
Brief Summary
To investigate the effect of allogeneic SLET and re-epithelialization after allogeneic SLET.
Detailed Description
Simple limbal epithelial transplantation (SLET) was introduced in 2012 by Sangwan and coworkers to overcome the issues mainly related to the cost of a GMP-certified product and ease of surgical manipu...
Eligibility Criteria
Inclusion
- Age between 10 to 90 years old
- The lesion eye has at least grade 2 limbal stem cell deficiency
- The lesion eye has limbal stem cell deficiency causing recurrent corneal erosion and neovascularization ingrowth
- The symptoms last for at least 6 months and do not improve with medication
Exclusion
- The symptoms improve spontaneously or with medication
- Someone who can not be examined regularly after the operation
- Poor prognosis
- Severe lagophthalmos or trichiasis that has not been corrected
- Ocular infection
Key Trial Info
Start Date :
July 5 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04021134
Start Date
July 5 2019
End Date
July 1 2025
Last Update
July 18 2019
Active Locations (2)
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1
National Taiwan University Hospital
Taipei, Taiwan, Republic of China, Taiwan, 10002
2
Department of Ophthalmology, National Taiwan University Hospital,
Taipei, Taiwan, 100