Status:
UNKNOWN
The Effects of Autologous SLET
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Limbal Stem-cell Deficiency
Eligibility:
All Genders
10-90 years
Brief Summary
This study aims to prospectively evaluate the therapeutic effects of autologous simple limbal epithelial transplantation for patients with limbal stem cell deficiency. The change of visual acuity, qua...
Detailed Description
Human corneal epithelial cells are stratified squamous cells that cover the corneal surface. These cells are regenerated from cells known as limbal stem cells (LSCs) that grow continuously and prolife...
Eligibility Criteria
Inclusion
- Age 10-90 years old
- The lesion eye has at least grade 2 limbal stem cell deficiency
- The lesion eye has limbal stem cell deficiency causing recurrent corneal erosion and neovascularization ingrowth
- The symptoms last for at least 6 months and do not improve with medication
Exclusion
- Symptoms improve spontaneously or under medication
- Someone who can not be examined regularly after the operation
- Someone with poor prognosis
- Severe lagophthalmos or trichiasis that has not been corrected
- Ocular infection
Key Trial Info
Start Date :
July 5 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04021875
Start Date
July 5 2019
End Date
July 1 2025
Last Update
July 16 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Taiwan University Hospital
Taipei, Taiwan, Republic of China, Taiwan, 10002