Status:
UNKNOWN
Study on Adaptive Radiotherapy and Multimodal Information of Cervical Cancer Assisted by Artificial Intelligence
Lead Sponsor:
The University of Hong Kong-Shenzhen Hospital
Conditions:
Cervical Cancer
Radiotherapy Side Effect
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
The standard treatment for non-operative cervical cancer is concurrent external radiation therapy and chemotherapy followed by brachytherapy. During the period of radiotherapy, organ movement and tumo...
Detailed Description
1. Introduction and background The standard treatment for non-operative cervical cancer is concurrent external radiation therapy and chemotherapy followed by brachytherapy. During the period of radiot...
Eligibility Criteria
Inclusion
- pathologically confirmed cervical squamous cell carcinoma or adenocarcinoma without treatment before;
- Age: ≥18 years old;
- The International Federation of Gynecology and Obstetrics(FIGO) stage: IB2 to IVA, or IVB with only para-aortic lymph node metastasis, refused or could not be treated by surgery;
- Eastern Cooperative Oncology Group(ECOG)score ≤2;
- good bone marrow, hematopoietic and liver and kidney function: absolute neutrophil count (ANC) ≥ 1.5 ☓ 109 / L, the platelet count ≥100 ☓ 109 / L, or hemoglobin \> 90 g/L, serum bilirubin \< 1.5 ☓ upper limit of normal reference value(ULN), aspartate aminotransferase(AST) and alanine aminotransferase(ALT)\< 2.5 ☓ ULN, serum creatinine clearance ≥ 50 ml/min.
- provide informed consent.
Exclusion
- women in pregnancy or nursing;
- contraindications to chemoradiotherapy;
- subjects participating in other clinical trials or participating in other clinical trials within 30 days;
Key Trial Info
Start Date :
December 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 30 2022
Estimated Enrollment :
122 Patients enrolled
Trial Details
Trial ID
NCT04022018
Start Date
December 18 2019
End Date
May 30 2022
Last Update
March 27 2020
Active Locations (1)
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1
HongKong University Shenzhen Hospital
Shenzhen, Guangdong, China, 518053