Status:
UNKNOWN
Pediatric Ventilation Weaning
Lead Sponsor:
São Paulo State University
Collaborating Sponsors:
Andréa Maria Cordeiro Ventura
Conditions:
Respiration, Artificial
Ventilator Weaning
Eligibility:
All Genders
29-15 years
Phase:
NA
Brief Summary
The hypothesis of the present study is that the use of Continuous Positive Airway Pressure (CPAP) plus PS can accelerate the weaning process and, consequently, shorten the MV. This multicenter, pragma...
Detailed Description
Mechanical ventilation (MV) is a widely used practice among Pediatric Intensive Care Units (PICUs) throughout the world. Data from multicenter studies reveal rates ranging from 20% to 64% use, lasting...
Eligibility Criteria
Inclusion
- Children who underwent mechanical ventilation for at least 24 hours in one of the participant PICUs
Exclusion
- Children dependent on mechanical ventilation and / or chronically supplemental oxygen;
- Children with do not resuscitation order (DNR)
- Children with neurological and neuromuscular disorders that may interfere with MV;
- Children with chronic lung diseases (such as cystic fibrosis, bronchopulmonary dysplasia, chronic obstructive pulmonary disease, with the exception of asthma);
- Children transferred from another PICU not included in the trial and whose weaning has already begun;
- Children whose cannulae have air leakage higher of 25% of inspiratory flow, without indication for cannula replacement.
Key Trial Info
Start Date :
October 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04023643
Start Date
October 1 2020
End Date
December 31 2023
Last Update
May 23 2022
Active Locations (5)
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1
Hospital das Clínicas de Marília - Unidade II
Marília, São Paulo, Brazil, 17500030
2
Hospital Municipal Vila Santa Catarina
São Paulo, Brazil, 04378-500
3
Hospital Municipal Dr. Moysés Deutsch
São Paulo, Brazil, 04948-970
4
Instituto da Criança do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, Brazil, 05403-000