Status:
COMPLETED
High Dose of Dual Therapy Plus Metronidazole for Helicobacter Pylori RescueTreatment
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Helicobacter Pylori Infection
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
Dual therapy containing high dose of proton pump inhibitor (PPI) and amoxicillin had showed excellent eradication results with Helicobacter pylori first-line treatment. However, no study has examined ...
Eligibility Criteria
Inclusion
- Participants with non-ulcer functional dyspepsia or peptic ulcer disease
- Ability and willingness to participate in the study and to sign and give informed consent
- Confirmed H. pylori infection and with previous treatment failure
Exclusion
- Less than 18 years old or older than 80 years
- With previous gastric surgery
- Major systemic diseases
- Pregnancy or lactation
- Allergy to any of the study drugs
- Administration of antibiotics, bismuth,antisecretory drugs in 8 weeks prior to inclusion
Key Trial Info
Start Date :
July 25 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 24 2021
Estimated Enrollment :
306 Patients enrolled
Trial Details
Trial ID
NCT04024527
Start Date
July 25 2019
End Date
May 24 2021
Last Update
September 28 2021
Active Locations (1)
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1
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, Shanghai Municipality, China, 200127