Status:
UNKNOWN
Feasibility Study Comparing Enteral vs Parenteral Nutritional Outcomes in Autologous Stem Cell Transplant Patients
Lead Sponsor:
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions:
Malignant Hematologic Neoplasm
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This study will highlight that Enteral Nutrition (EN) is as effective in nutritionally supporting as Parenteral Nutrition (PN) in this group of patients undergoing an autologous hematopoietic stem cel...
Detailed Description
This will be a pilot open randomized study. The study will be conducted at the inpatient setting at London Health Sciences Centre in London, ON. Forty patients will be randomized in permutated blocks ...
Eligibility Criteria
Inclusion
- All adult patients aged 18 to 75 years.
- Patients admitted to Victoria Hospital undergoing AHSCT on C7 unit.
- Patient consented to participate in the study
- Patients diagnosed with the following conditions: Non- Hodgkin's Lymphoma (all types), Hodgkin's Lymphoma (all subtypes) and Multiple Myeloma
- Patients receiving any of the following: Conditioning chemotherapy: Melphalan, Etoposide/Melphalan, or Carmustine, Etoposide, Cytarabine, Melphalan
- Have a functional Gastrointestinal tract
Exclusion
- Intestinal obstruction
- Patients with nasal deformities, tumors of nasal tracts or upper nare obstruction.
- Patients with active bacteremia while proceeding with transplant
- Patients with active malignancy of Upper GI tract, not in remission as evidenced by recent imaging studies (\< 4 weeks)
- Patients with any GI bleeding, paralytic ileus, obstruction, or any other GI condition which excludes use of the GI system for nutritional support as these patients will require PN feeding only and cannot be randomized
Key Trial Info
Start Date :
August 20 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04024618
Start Date
August 20 2019
End Date
December 31 2020
Last Update
March 31 2020
Active Locations (1)
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1
London Health Sciences Centre-Victoria Hospital
London, Ontario, Canada, N6A 5W9