Status:

UNKNOWN

Improving in Vitro Fertilization in Women With Poor Ovarian Response

Lead Sponsor:

Barzilai Medical Center

Conditions:

Poor Ovarian Response

Ovarian Insufficiency

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

Improving the results of in vitro fertilization in women with poor ovarian response and early ovarian insufficiency

Detailed Description

BACKGROUND: Mechanical disruption of the Hippo signaling pathway in the ovaries can increase the likelihood of pregnancy and childbirth in women with early ovarian insufficiency. The method may also "...

Eligibility Criteria

Inclusion

  • Volunteers with poor ovarian response to standard fertility treatments according to the criteria of the European Fertility Association (ESHRE).
  • Diagnosis of early ovarian insufficiency or symptoms that predict early ovarian insufficiency (imminent) seeking to become pregnant.

Exclusion

  • Volunteers with
  • Severe endometriosis diagnosed with laparoscopy.
  • Previous major surgery involving ovaries.
  • Ovarian cancer.
  • Female reproductive malformations.
  • Contraindications for laparoscopic surgery.

Key Trial Info

Start Date :

January 14 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2022

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04024722

Start Date

January 14 2020

End Date

July 31 2022

Last Update

July 28 2021

Active Locations (1)

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1

Barzilay University Medical Center

Ashkelon, Israel