Status:
COMPLETED
Transdermal Iontophoresis of Vitamin B12 Under Three Different Skin Preparations
Lead Sponsor:
James J. Peters Veterans Affairs Medical Center
Conditions:
Macrocytic Anemia With Vitamin B12 Deficiency
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
STUDY DESIGN: Phase I Clinical Trial The researchers set out to assess the effectiveness of transdermal iontophoretic administration of Vitamin B12 (V.B12) under three different skin preparatory condi...
Detailed Description
In order to quantify the changes in skin permeability to drugs delivered by ION under three different preparatory conditions, we used V.B12 as a model substance. Its choice was dictated by its inheren...
Eligibility Criteria
Inclusion
- Able-bodied,
- Male or female,
- Between the ages of 18-80 years old.
Exclusion
- Previous adverse reaction or hypersensitivity to electrical stimulation,
- Pregnancy (women who are sexually active and of childbearing potential must utilize a method of contraception and agree to maintain a contraceptive method until completion of the study),
- Inability to provide informed consent,
- History of ingrown hair folliculitis after shaving or epilation,
- Allergy to Sodium Lauryl Sulfate, Oleic acid, Silver Chloride, Agarose Gel, Methylcobalamin, Citric Acid, Isopropyl alcohol, Benzocaine, Polyethylene film, Polyethylene Glycol solvent,
- Concurrent illness with fever,
- Concurrent participation in a research study,
- VA employee.
Key Trial Info
Start Date :
October 5 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2018
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04027959
Start Date
October 5 2017
End Date
November 1 2018
Last Update
December 14 2020
Active Locations (1)
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1
James J Peters VA Medical Center
The Bronx, New York, United States, 10468