Status:

RECRUITING

Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients

Lead Sponsor:

Nantes University Hospital

Conditions:

Cutibacterium Acnes Infection

Eligibility:

MALE

18+ years

Phase:

PHASE3

Brief Summary

Infections on joint replacements remain one of the most serious complications of orthopaedic surgery. Despite improvements in skin preparation and antibiotic prophylaxis procedures, the risk of infect...

Eligibility Criteria

Inclusion

  • Male patients, Adult patients,
  • Patient without a history of surgical intervention on the operated shoulder,
  • Patient managed for glenohumeral, partial (cup or anatomical hemi- arthroplasty) or total (anatomical or inverted) glenohumeral arthroplasty placement for primary osteoarthritis, or secondary to necrosis, massive rotator cuff tear or old fracture.
  • Patients affiliated to a social security system
  • Patients who have given their informed and written consent

Exclusion

  • Patient with arthroplasty for resumption of previous shoulder surgery or failure of arthroplasty
  • Patient with arthroplasty for acute trauma
  • Patient on immunosuppressantsimmunosuppressive drugs
  • Patient with inflammatory rheumatism
  • Patient with progressive cancer pathology
  • Allergies or intolerances concerning the modalities of selected skin preparations (Povidone Iodine, hypersensitivity to benzoyl peroxide)
  • Dermatological pathologies in the area to be treated
  • Acne treatment in the area to be treated within four weeks before inclusion
  • Patient without possible help from a third party for the application of Cutacnyl® 5% in the intervention group if necessary
  • Major under guardianship
  • Patient under the protection of justice
  • Patient not covered by social security

Key Trial Info

Start Date :

June 19 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2029

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT04028401

Start Date

June 19 2020

End Date

June 1 2029

Last Update

May 1 2025

Active Locations (6)

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Page 1 of 2 (6 locations)

1

CHU d'Angers

Angers, France, 49933

2

CHU de Brest

Brest, France, 29609

3

CHU de Limoges

Limoges, France, 87000

4

CHU de Nantes

Nantes, France, 44093