Status:
COMPLETED
Measuring Blood Flow in the Brain After Epileptic Activity
Lead Sponsor:
Rijnstate Hospital
Collaborating Sponsors:
University of Twente
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions:
Epilepsy
Depression
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
In this clinical trial, postictal phenomena (i.e., headache, delirium) will be investigated after administration of acetaminophen and nimodipine in depressed patients receiving electroconvulsive thera...
Detailed Description
Postictal phenomena, such as sensory, motor or memory deficits, headache, delirium, and psychosis, are common manifestations after electroconvulsive therapy (ECT) induced seizures. Also, postictal phe...
Eligibility Criteria
Inclusion
- Adulthood (age \> 17 years);
- Current clinical diagnosis of depressive episode (unipolar, bipolar, schizoaffective);
- Willingness and ability to give written informed consent and willingness and ability to understand, to participate and to comply with the study requirements.
Exclusion
- Known adverse or allergic reactions to acetaminophen or nimodipine;
- Chronic use of acetaminophen, calcium-antagonists or NSAID's that cannot be interrupted for less than two days before the ECT-session;
Key Trial Info
Start Date :
December 5 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 15 2023
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT04028596
Start Date
December 5 2019
End Date
April 15 2023
Last Update
November 18 2023
Active Locations (1)
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1
Rijnstate Hospital
Arnhem, Gelderland, Netherlands, 6815 AD