Status:

COMPLETED

FLT PET: A Pilot Study in Lymphoma Patients

Lead Sponsor:

The Hospital for Sick Children

Conditions:

Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

Eligibility:

All Genders

1-18 years

Brief Summary

Background: Residual masses on follow-up surveillance imaging are frequently detected in paediatric patients with Hodgkin's lymphoma and non-Hodgkin's lymphoma. The residual mass may consist of inflam...

Detailed Description

This is a prospective pilot study evaluating the clinical use of FLT PET in paediatric patients with Hodgkin's lymphoma (HL) or non-Hodgkin's lymphoma (NHL). The overall objective of this trial is to ...

Eligibility Criteria

Inclusion

  • SickKids Hospital patient of any gender or race
  • Participants who are able to undergo imaging procedures without general anaesthesia or sedation
  • Patient's or the patient's parents'/guardians' written informed consent prior to participation
  • Previous FDG PET scan with at least one documented equivocal finding (i.e. SUV ≥ 2.0, but \< 3.5) and no other finding(s) that is strongly suggestive of malignancy. The lesion(s) must have a minimum size of 1 cm in diameter by any CIM in order to address the spatial resolution limitations of the PET scanner.

Exclusion

  • Patients who are pregnant or nursing
  • Medically unstable or critically ill
  • Lack of informed consent

Key Trial Info

Start Date :

July 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2014

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT04028804

Start Date

July 1 2011

End Date

December 1 2014

Last Update

July 23 2019

Active Locations (1)

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1

The Hospital for Sick Children

Toronto, Ontario, Canada, M5G 1X8