Status:

COMPLETED

Penthrox in Rezūm BPH

Lead Sponsor:

Dean Elterman

Conditions:

Pain

BPH

Eligibility:

MALE

18+ years

Phase:

PHASE4

Brief Summary

Open-labeled, single-centre study

Detailed Description

Patients who have elected Convective Thermal Therapy using Rezūm System for the management of their BPH and fulfilled inclusion and exclusion criteria will sign informed consent form for the study. Pa...

Eligibility Criteria

Inclusion

  • Male subjects of ≥ 18 years of age
  • Patient who has elected Convective Thermal Therapy using Rezūm System for the management of their benign prostatic hyperplasia.
  • No contra-indication on using Methoxyflurane inhaler (Penthrox™).
  • Willing and able to accurately complete the required questionnaires.
  • Willing and able to provide signed and dated informed consent.

Exclusion

  • Ongoing use of analgesic agents for chronic pain.
  • Concomitant use of nephrotoxic agents.
  • INR \> 4.
  • Use of Methoxyflurane inhaler (Penthrox™) within the previous 3 months.
  • Known allergy to Lorazepam, Percocet/ Oxycodone, or Xylocaine® gel.
  • Known personal or familial hypersensitivity to Methoxyflurane inhaler (Penthrox™) or other halogenated anesthetics.
  • Clinically significant respiratory depression, cardiovascular instability, renal or hepatic impairment.
  • An altered level of consciousness, due to any cause, including head injury, drugs, or alcohol.
  • Known or genetically susceptible to malignant hyperthermia or a history of severe adverse reactions in either patient or relatives.
  • A history of liver dysfunction after previous Methoxyflurane inhaler (Penthrox™) use or other halogenated anesthetics.

Key Trial Info

Start Date :

September 10 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 14 2020

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04029012

Start Date

September 10 2019

End Date

February 14 2020

Last Update

January 24 2022

Active Locations (1)

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Can-Am HIFU Inc

Toronto, Ontario, Canada