Status:
UNKNOWN
Post-polypectomy Surveillance Interval In High-risk Subjects After Screening Colonoscopy
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Surveillance Colonoscopy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
With many countries initiating population colorectal cancer (CRC) screening, including Hong Kong, more robust guidance for surveillance interval is required to maximize subject's benefit with optimal ...
Detailed Description
The aim of the study is to determine whether the risk of metachronous advanced neoplasia increases if surveillance interval was beyond the current recommendation of 3 years for high-risk subjects with...
Eligibility Criteria
Inclusion
- Advanced adenoma at screening colonoscopy
- ≥3 adenomas at screening colonoscopy
- Cecal intubation at screening colonoscopy (preferably documented by images/video of the apendiceal orifice and the ileocecal valve; but not required)
- Complete excision of all polyps at screening colonoscopy findings (after review of endoscopy reports and pathological specimens)
- Eligible for surveillance in out-patient setting
Exclusion
- Lack of consent
- Incomplete screening colonoscopy
- Incomplete endoscopic excision of polyps at screening colonoscopy
- CRC at screening colonoscopy
- Polyps requiring Endoscopic Submucosal Dissection at screening colonoscopy
- Serrated polyps ≥ 10 mm in diameter at any colorectal location or ≥ 5 mm if located proximal to the splenic flexure on screening colonoscopy
- Genetic cancer syndrome (adenomatous or serrated polyposis syndrome; Lynch or Lynch-like syndrome)
- Inflammatory bowel disease
- History of surgical colon resection for any reason
- Severe co-morbidity with reduced life expectancy (NYHA 3-4)
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2019
Estimated Enrollment :
270 Patients enrolled
Trial Details
Trial ID
NCT04034563
Start Date
February 1 2019
End Date
December 31 2019
Last Update
July 26 2019
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Endoscopy Center, Prince of Wales Hospital
Hong Kong, Hong Kong
2
S.H. Ho Centre for Digestive Health, Prince of Wales Hospital
Hong Kong, Hong Kong