Status:
UNKNOWN
Endophthalmitis Post Intravitreal Injections
Lead Sponsor:
Unity Health Toronto
Conditions:
Endophthalmitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Intravitreal injection (IVI) is an ophthalmological procedure used worldwide to treat ocular conditions. Its use has been steadily increasing for several years, because this method of drug delivery mi...
Detailed Description
Background The use of intravitreal injections (IVIs) has been steadily increasing for several years, because this method of drug delivery minimizes systemic exposure and allows for intraocular drug le...
Eligibility Criteria
Inclusion
- Patients 18 years and older
- Intravitreal injections other than intravitreal steroids within the last 2 weeks
- Diagnosed with presumed infectious endophthalmitis: patients presenting with vision loss and hypopyon
- Visual acuity of light perception or better
- Safety concern by the treating physician for patients enrolled in the study. That is to say, if the physician feels a patient's outcomes would be better with one intervention over the other, this patient should not be enrolled in the study.
Exclusion
- Prior intraocular surgery in the study eye within the last 3 months
- Prior penetrating ocular trauma
- Bleb or prior glaucoma filtration surgery in the study eye
- Patients with other ocular conditions limiting vision in the study eye other than the retinal pathology for which they receive intravitreal injections for e.g. anterior segment pathology, retinal detachments, end-stage glaucoma
- Previous vitreo-retinal surgery.
- Unwilling or unable to follow or comply with all study-related procedures or sign consent form
Key Trial Info
Start Date :
March 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2024
Estimated Enrollment :
310 Patients enrolled
Trial Details
Trial ID
NCT04035369
Start Date
March 1 2020
End Date
July 1 2024
Last Update
May 11 2023
Active Locations (1)
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1
St. Michael's Hospital Eye Clinic
Toronto, Ontario, Canada, M5C2T2