Status:

NOT_YET_RECRUITING

129Xe MRI in Pediatric Population With BPD

Lead Sponsor:

Xemed LLC

Collaborating Sponsors:

Children's Hospital of Philadelphia

Conditions:

Bronchopulmonary Dysplasia

Eligibility:

All Genders

Up to 1 years

Phase:

PHASE1

Brief Summary

Hyperpolarized (HP) gas magnetic resonance imaging (MRI) of the lungs offers additional information that cannot be obtained with CT scan, the current gold standard for imaging this disorder. As a noni...

Detailed Description

The most common respiratory complication of preterm birth, bronchopulmonary dysplasia (BPD), defined by a clinically assessed need for supplemental oxygen support at 36 weeks post-menstrual age, has a...

Eligibility Criteria

Inclusion

  • Infants admitted to the NICU at the Children's Hospital of Philadelphia with bronchopulmonary dysplasia who are followed by the Chronic Lung Disease Program.
  • Subjects mechanically ventilated either via and endotracheal tube or via a tracheostomy.
  • Subjects already receiving sedation as part of clinical care.

Exclusion

  • \- Infants whom the primary care team deems to be unstable for transport to MRI

Key Trial Info

Start Date :

August 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2031

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04035629

Start Date

August 1 2026

End Date

December 31 2031

Last Update

April 4 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104