Status:
ACTIVE_NOT_RECRUITING
Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers
Lead Sponsor:
Vanderbilt University Medical Center
Collaborating Sponsors:
University of Calgary
Conditions:
Ehlers-Danlos Syndrome
Anesthesia, Local
Eligibility:
All Genders
18+ years
Brief Summary
Local anesthetic resistance is commonly reported by patients with EDS. However, there are no objective data on the occurrence of local anesthetic resistance in EDS patients and in healthy volunteers. ...
Detailed Description
There was a prior large online questionnaire to better understand the issues around local anesthetic resistance. By November 2018, 933 EDS patients (total 1059 respondents) completed the survey, 99.2%...
Eligibility Criteria
Inclusion
- EDS patients, clinically diagnosed hypermobile EDS based on 2017 criteria
- EDS patients with genetically proven non-hypermobile EDS
- Healthy participants, no EDS
- Able and willing to provide informed consent
Exclusion
- Known allergy to Lidocaine or Bupivacaine
- Unable to provide informed consent
Key Trial Info
Start Date :
July 26 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2029
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT04036305
Start Date
July 26 2019
End Date
December 31 2029
Last Update
October 14 2025
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232