Status:
COMPLETED
Comparison of Tear Evaporation Rate With DAILIES TOTAL1 and Biotrue ONEday
Lead Sponsor:
University of Waterloo
Conditions:
Evaporative Dry Eye
Eligibility:
All Genders
17+ years
Phase:
NA
Brief Summary
The purpose of this pilot study is to compare the effect of DAILIES TOTAL1, a low water content silicone hydrogel lens, and Biotrue ONEday, a high water content hydrogel lens, on the rate of tear evap...
Eligibility Criteria
Inclusion
- Is at least 17 years of age and has full legal capacity to volunteer;
- Has read and signed an information consent letter;
- Is willing and able to follow instructions and maintain the appointment schedule;
- Has worn soft contact lenses for a minimum of 6 months;
- Currently wears soft contact lenses for at least 4 days per week and 8 hours per day;
- Has an acceptable fit and comfort with both study contact lenses in the powers available;
- Has less than or equal to 1.00DS difference between eyes in their habitual contact lenses;
- Is willing to be awake for at least 2 hours before visit 2;
- Is willing to not wear eye makeup on the day of visit 2 and 3;
- Is willing to not use eye drops or artificial tears on the day of visits 1, 2, and 3;
- Has a wearable pair of spectacles.
Exclusion
- Is participating in any concurrent clinical or research study;
- Has any known active\* ocular disease and/or infection;
- Has a systemic condition that in the opinion of the investigator may affect a study outcome variable;
- Is using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable;
- Has known sensitivity to sodium fluorescein dye;
- Is pregnant, lactating or planning a pregnancy at the time of enrolment (by verbal confirmation at the screening visit);
- Is aphakic;
- Has undergone refractive error surgery;
- Has a known sensitivity to petroleum jelly (Vaseline);
- Has epilepsy and/or a sensitivity to flashing lights;
- Wears toric contact lenses;
- Has any physical impairment that would interfere with holding the evaporimeter;
- Has taken part in another research study within the last 14 days.
Key Trial Info
Start Date :
August 7 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 26 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04037969
Start Date
August 7 2019
End Date
November 26 2019
Last Update
April 23 2021
Active Locations (1)
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1
Centre for Ocular Research & Education
Waterloo, Ontario, Canada, N2L 3G1