Status:
UNKNOWN
Transport of Satiety Factors Into the CSF
Lead Sponsor:
University Hospital Tuebingen
Conditions:
Obesity
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The blood-brain barrier regulates the passage of peripheral built appetite-suppressing hormones from the blood to the brain and informs the brain about the nutritional- and energy status. The aim of ...
Eligibility Criteria
Inclusion
- patients with cerebrospinal fluid drainage
Exclusion
- Women during pregnancy and lactation
- Participation in other interventional clinical trials
- severe infection within the last 4 months
- intake of central effective substances which may interact with the transport processes to be investigated
- hypersensitivity to any of the substances used
- diabetes mellitus
- Patients with CSF results indicative of infectious diseases within the central nervous system
- subjects with hemoglobin Hb \<10 g / dl
- Patients with a neurosurgical disorder suspected of having a blood-brain barrier disorder
Key Trial Info
Start Date :
July 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2023
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04038086
Start Date
July 15 2019
End Date
June 1 2023
Last Update
March 28 2022
Active Locations (1)
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1
University of Tuebingen, Department of Internal Medicine IV
Tübingen, Germany, 72076