Status:
COMPLETED
The Genetics of Adipose Tissue Function and Its Link to Type 2 Diabetes and Heart Disease
Lead Sponsor:
Royal Devon and Exeter NHS Foundation Trust
Collaborating Sponsors:
University of Exeter
NIHR Exeter Clinical Research Facility
Conditions:
Diabetes Mellitus
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Obesity is a major risk factor for Type 2 diabetes. However, two obese people of the same height and weight can have very different risks of the condition. As a greater proportion of the population is...
Detailed Description
Introduction: Diabetes is the most common chronic metabolic disease and is a major source of morbidity and mortality. It is one of the biggest healthcare challenges facing the United Kingdom's (UK) N...
Eligibility Criteria
Inclusion
- Demographics: Age 18-75 inclusive
- Ethnicity: Reflective of local demographic
- Mental capacity: Willing and able to provide informed consent
Exclusion
- Medical history: History of bariatric surgery and recent significant weight loss/gain (+/- 3 kgs/ half a stone in the last 3 months); connective tissue disease, pregnancy and lactation (if women are recruited).
- Medications: Currently prescribed oral/IV corticosteroid treatment or loop diuretics (furosemide, bumetanide), antiplatelet and anticoagulation medication, methotrexate
- Mental capacity: Unable/unwilling to provide informed consent.
Key Trial Info
Start Date :
March 7 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 20 2021
Estimated Enrollment :
207 Patients enrolled
Trial Details
Trial ID
NCT04040595
Start Date
March 7 2019
End Date
May 20 2021
Last Update
June 8 2021
Active Locations (1)
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1
Royal Devon and Exeter NHS Foundation Trust / University of Exeter
Exeter, Devon, United Kingdom, EX2 5DW