Status:
RECRUITING
Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Conditions:
Subarachnoid Hemorrhage
Critical Illness
Eligibility:
All Genders
16+ years
Phase:
NA
Brief Summary
Patients with subarachnoid hemorrhage are prone to suffer from dysnatriemia. Evidence shows that hyponatriemia is associated with increased incidence of vasospasm, brain swelling and mortality in thes...
Detailed Description
Background: Despite ongoing advances in critical care mortality and morbidity of patients with subarachnoid hemorrhage remains high. Secondary brain injuries related to cerebral vasospasm and consecut...
Eligibility Criteria
Inclusion
- All adult patients suffering from non-traumatic subarachnoid haemorrhage.
Exclusion
- Patients with major intra-cranial trauma
- Diagnosis of an AV-malformation as the source of subarachnoid hemorrhage on the primary CT/MRI or angiography
- More than 24 hours after diagnosis of subarachnoid haemorrhage as diagnosed by cerebral imaging (CT scan or MRI)
- Patients with clear limitation to therapy at hospital admission (eg ICU admission for evaluation of organ donation)
- Declining of informed consent
Key Trial Info
Start Date :
May 24 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
320 Patients enrolled
Trial Details
Trial ID
NCT04043598
Start Date
May 24 2022
End Date
July 1 2026
Last Update
December 18 2025
Active Locations (3)
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1
Department of perioperative Intensive Care Medicine
Sankt Gallen, Canton of St. Gallen, Switzerland, 9007
2
Department of Intensive Care, Bern University Hospital and University of Bern, Bern, Switzerland
Bern, Switzerland, 3010
3
Department of Intensive Care Medicine
Geneva, Switzerland, 1205