Status:
COMPLETED
Platelet-rich Fibrin and Autogenous Bone vs Membrane and Autogenous Bone in Intrabony Defects
Lead Sponsor:
G. d'Annunzio University
Conditions:
Periodontal Bone Loss
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Currently, the most positive documented outcomes of periodontal regenerative therapy (PRT) in intrabony defects (IBDs) have been achieved with a combination of bone grafts ( BGs) and a regeneration ma...
Detailed Description
This is a prospective, randomized and controlled clinical trial designed to evaluate the clinical and radiographic outcomes 12 months after two treatment modalities of IBDs: PRF + ABG into defects in ...
Eligibility Criteria
Inclusion
- a full-mouth plaque score (FMPS) 25 and a full-mouth bleeding score (FMBS) 26 \< 20% at the time of surgery
- to have at least 20 teeth,; at least 1 tooth exhibiting vertical bone loss detected by radiographic examination (alveolar crest level (ACL) - bottom of the defect (BD) distance - -Bone defect depth (BDD) ≥ 4 mm and a probing pocket depth (PPD) ≥ 5mm when evaluated 12 weeks after phase I non- surgical therapy \[ scaling and root planing ( SRP)\]
Exclusion
- no systemic diseases
- no medications affecting periodontal status during the previous 6 months
- not pregnant or lactating; non-smoker
- no periodontal therapy in the 2 previous years, no inadequate endodontic treatment, no dental mobility
Key Trial Info
Start Date :
June 10 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 15 2023
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT04043754
Start Date
June 10 2018
End Date
July 15 2023
Last Update
July 1 2024
Active Locations (1)
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1
G. d'Annunzio University
Chieti, CH, Italy, 66100