Status:
COMPLETED
Calorie Restriction Intervention Induces Enterotype-associated BMI Loss in Nonobese Individuals
Lead Sponsor:
BGI-Shenzhen
Conditions:
Healthy Volunteer
Eligibility:
All Genders
22-53 years
Phase:
NA
Brief Summary
Calorie restriction (CR), which has the potential effect on weight loss and blood amino acids, has been demonstrated to associate with gut microbiota in humans, especially in obese individuals. Howeve...
Detailed Description
1. Volunteer Recruitment Volunteer-wanted posters were propagated at the China National Gene Bank in Shenzhen from March to April 2017. A non-obese healthy volunteer was considered if his/her BMI ...
Eligibility Criteria
Inclusion
- BMI less than 28 kg/m2 and more than 18 kg/m2;
- without antibiotics in the recent 2 months;
- regular eating and lifestyle patterns;
- no international travel in the recent 3 month;
- without hypertension, diabetes mellitus, gastrointestinal disease and other severe auto-immune disease;
- without prebiotic or probiotic supplements in the recent 2 months;
Exclusion
- with antibiotics in the recent 2 months;
- Failure to comply with experimental requirement;
Key Trial Info
Start Date :
April 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 4 2018
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT04044118
Start Date
April 1 2017
End Date
February 4 2018
Last Update
August 5 2019
Active Locations (1)
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1
BGI-Shenzhen, Guangdong, China
Shenzhen, Guangdong, China, 518083