Status:
COMPLETED
TIPS Plus Transvenous Obliteration for Gastric Varices
Lead Sponsor:
University of Illinois at Chicago
Conditions:
Cirrhosis, Liver
Hypertension, Portal
Eligibility:
All Genders
18+ years
Brief Summary
Variceal hemorrhage (VH) from gastric varices (GVs) results in significant morbidity and mortality among patients with liver cirrhosis. In cases of acute bleeding, refractory bleeding, or high risk GV...
Detailed Description
Liver cirrhosis-or scarring of the liver-occurs with a worldwide prevalence approximating 4.5-9.5%, affecting hundreds of millions of people. Cirrhosis results in 2% of all global mortality, approxima...
Eligibility Criteria
Inclusion
- Aged ≥ 18 years
- Ability to provide written consent
- Endoscopically proven acute or recurrent VH from GVs, or high risk GVs
Exclusion
- Prior indwelling TIPS
- Prior endovascular obliteration procedure
- Elevated heart pressures (left or right)
- Heart failure or severe valvular insufficiency
- Severe pulmonary hypertension
- Rapidly progressive liver failure
- Severe or uncontrolled hepatic encephalopathy
- Uncontrolled systemic infection or sepsis
- Unrelieved biliary obstruction
- Polycystic liver disease
- Extensive primary or metastatic hepatic malignancy
- Severe uncontrolled coagulopathy
- Pregnancy
Key Trial Info
Start Date :
April 4 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 18 2024
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT04044248
Start Date
April 4 2019
End Date
June 18 2024
Last Update
November 19 2024
Active Locations (1)
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1
University of Illinois at Chicago
Chicago, Illinois, United States, 60612