Status:
UNKNOWN
Liquorice and Salivary Cortisol
Lead Sponsor:
Umeå University
Conditions:
Cushing Syndrome
Hypercortisolism
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Salivary cortisol is used as a diagnostic analysis in the investigation of suspected Cushings' syndrome. This study evaluates if liqourice intake increases salivary cortisol in healthy individuals. La...
Eligibility Criteria
Inclusion
- Men and women 18-65 years.
Exclusion
- Known pituitary or adrenal disease
- Medication with glucocorticoids (incl. inhalation, nasal, dermal)
- Known hypertension or blood pressure \>140/90 at screening
- tobacco use
- Subjective problems in oral mucosa or saliva
- Abnormal diurnal rhythm (awake 03:00 - 05:30)
- Difficulties taking liqourice for 3 weeks or refraining from liqourice during 4 weeks
Key Trial Info
Start Date :
October 16 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04045015
Start Date
October 16 2018
End Date
December 31 2020
Last Update
August 5 2019
Active Locations (1)
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1
Department of Public Health and Clinical, Umeå University
Umeå, Sweden, 901 85