Status:
UNKNOWN
A Study on the Microcirculatory Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With COPD
Lead Sponsor:
Zhejiang Chinese Medical University
Collaborating Sponsors:
The Third Affiliated hospital of Zhejiang Chinese Medical University
The First Affiliated Hospital of Zhejiang Chinese Medical University
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
20-75 years
Brief Summary
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches. Particularly, previous ...
Detailed Description
This study will include 40 patients diagnosed with chronic obstructive pulmonary disease (COPD) and 80 healthy volunteers. Laser doppler examination will be adopted to assess the microcirculatory char...
Eligibility Criteria
Inclusion
- Inclusion criteria for the COPD group
- Patients should meet the above diagnostic criteria, and the severity of COPD is in the stage of GOLD 2 or 3 based on pulmonary function testing;
- COPD patients in the stable phase, who present with mild symptoms of cough, expectoration and short breath;
- 35 ≤ age ≤75 years, male or female;
- Patients have clear consciousness and could communicate with others normally;
- Patients could understand the full study protocol and have high adherence.Written informed consent is signed by themselves or their lineal kin.
- Inclusion criteria for health volunteers
- Healthy volunteers who could provide a recent (in the past 3 month) medical examination report to confirm they have not any cardiovascular, respiratory, digestive, urinary, hematological, endocrine and neurological disease;
- age ≥20 years, male or female;
- Participants have clear consciousness and could communicate with others normally;
- Participants could understand the full study protocol and have high adherence .Written informed consent is signed by themselves or their lineal kin.
Exclusion
- Exclusion criteria for the COPD group
- Patients who fail to meet the diagnostic criteria for COPD, or COPD patients in the phase of acute exacerbation;
- Patients have the following complications, which includes pneumonia, bronchial asthma, bronchiectasis, active tuberculosis, pneumothorax, chest trauma, tumors of the lung or thorax, and other confirmed respiratory diseases;
- Patients have concomitant conditions of heart diseases, such as chronic stable angina pectoris (CSAP);
- Patients have serious concomitant conditions and fail to treat them effectively, such as diseases of the digestive, urinary, respiratory, hematological, and nervous system;
- Patients have mental illness, severe depression, alcohol dependence or history of drug abuse;
- Pregnant or lactating patients; Patients are participating in other trials.
- Exclusion criteria of health volunteers
- Participants have sudden severe diseases during the trial, such as cardiovascular diseases, liver diseases, kidney diseases, urinary diseases and hematological diseases.
- Participants have mental illness, severe depression, alcohol dependence or history of drug abuse;
- Pregnant or lactating participants ;
- Participants are participating in other trials.
Key Trial Info
Start Date :
February 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2021
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04045418
Start Date
February 1 2020
End Date
December 1 2021
Last Update
January 22 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
the Third affiliated hospital of Zhejiang Chinese Medical university
Hanzhou, Zhejiang, China, 310000