Status:
COMPLETED
Cerebral Oxygenation During Gait in Elderly
Lead Sponsor:
Centre Hospitalier Régional d'Orléans
Conditions:
Cerebral Oxygenation
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
Ageing is accompanied by a cognitive decline altering gait and increasing the risk of falling. Physical activity could reduce this cognitive decline by an improvement in the oxygen supply to the brain...
Detailed Description
The main aim of the study is to determine the effect of the physical activity level on variations of the pre-frontal oxygenation during walking and during a dual task in elderly. The other aims are to...
Eligibility Criteria
Inclusion
- men and women non active young people and men and women non active old people : practice less than one hour of physical activity per week
- men and women active old people: practice at least 3 hours of physical activity per week
- Non-Inclusion Criteria :
- For all subjects:
- Resting electrocardiographic abnormality, Systolic blood pressure \>16
- Heart disease, recent and unusual shortness of breath or needing several pillows to sleep at night, effort/rest chest pain, palpitations with effort, history of discomfort with effort
- Respiratory failure
- Disabling rheumatological pathology for walking
- Neuro-progressive disease or sequelae
- Perceptual disorders
- Medication (neuroleptics, psychotropic treatment modifying alertness) potentially having an impact on walking
- Thickness of the skin fold at the vast lateral area greater than 15 mm
- Inability of the volunteer to perform the Random Generation of Numbers task for at least 1 min or frequency of enunciation numbers during the Random Generation of Numbers task \> 4/s
- Refusal to sign informed consent
- For the young sedentary group (woman and man) and the senior group (woman and man, sedentary and active):
- Subjective health \> 3 out of 5
- For the senior group (woman and man, sedentary and active):
- Mini-Mental State Evaluation (MMSE) score \< 24
- Geriatric Depression Scale (GDS) score \> 10
- For the Parkinson group (woman and man):
- Presence of a freezing or clinically embarrassing festination (walking disorder)
- Score of Hoehn and Yahr ≥III
Exclusion
- Inability of the volunteer to walk on the treadmill at a speed of 3 km/h without assistance (stand at the helm or ask for help)
Key Trial Info
Start Date :
February 25 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 20 2021
Estimated Enrollment :
117 Patients enrolled
Trial Details
Trial ID
NCT04045444
Start Date
February 25 2019
End Date
April 20 2021
Last Update
September 1 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
CHR Orléans
Orléans, France, 45067