Status:
COMPLETED
Safety of Inhaled Hydrogen Gas Mixtures in Healthy Volunteers
Lead Sponsor:
Boston Children's Hospital
Conditions:
Healthy
Eligibility:
All Genders
18-35 years
Phase:
PHASE1
Brief Summary
Hydrogen gas may decrease the degree or incidence of brain injury following ischemia. The purpose of this study is to determine the safety and tolerability of inhaled hydrogen gas at the dose exposure...
Detailed Description
Inhaled hydrogen gas (H2) has been shown to have significant protective effects on ischemic organs. Clinical trials abroad have shown promise that treatment of patients suffering from stroke, cardiac ...
Eligibility Criteria
Inclusion
- Age 18 to 35
- Able to remain inpatient for duration of admission (24-72 hours)
Exclusion
- History of any chronic illness, including respiratory disorders such as asthma, chronic obstructive pulmonary disease, prior acute lung injury or acute respiratory distress syndrome;
- Inflammatory disorders, such as lupus erythematosus, inflammatory bowel disease;
- Heritable disorders, such as trisomy 21, cystic fibrosis;
- Mitochondrial disorders;
- Currently smoking cigarettes or have a history of smoking cigarettes;
- The regular use of prescription medications (except for contraceptive medications) within 30 days of enrollment;
- Any lifetime inpatient hospitalization for respiratory illness;
- Pregnancy.
Key Trial Info
Start Date :
October 26 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2021
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT04046211
Start Date
October 26 2020
End Date
May 1 2021
Last Update
May 6 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Boston Children's Hospital
Boston, Massachusetts, United States, 02115