Status:

COMPLETED

Evaluation of Serum Taurine as a Prognostic Marker for Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant

Lead Sponsor:

Ain Shams University

Conditions:

Taurine

Eligibility:

All Genders

18-70 years

Brief Summary

Although the hepatoprotective properties of taurine are well established, however the correlation of the perioperative serum level of this amino acid in the recipients of living donor liver transplant...

Detailed Description

* All selected adult patients undergoing LDLT will be admitted to the ICU post LDLT * Preoperative assessment and preparation will be done according to the standard protocol of the hospital. After ful...

Eligibility Criteria

Inclusion

  • Recipient age ≥18 years.
  • Donor age between 18 and 45 years
  • ABO group compatibility with the recipient
  • Normal psychological workup.

Exclusion

  • Recipients patients with pre-existing renal failure requiring hemodialysis or continuous hemofiltration, glomerular filtration rate ≤ 30 ml /min by renal scan, ..
  • Re-transplant
  • HA1C \> 7%
  • Pregnancy.
  • Donors with fatty liver.
  • Estimated remnant liver volume for donor is \< 30% of total liver volume.
  • Donor body mass index \> 28 kg/m².
  • Donor with abnormal biliary anatomy.
  • Donor with steatosis \> 10%.

Key Trial Info

Start Date :

August 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 30 2020

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04047043

Start Date

August 1 2019

End Date

May 30 2020

Last Update

August 24 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hanaa El Gendy

Cairo, Ain Shams University Specialized Hospital, Egypt