Status:
COMPLETED
The Promotion of Physical Activity for the Prevention of Alzheimer's Disease in Adults With Down Syndrome
Lead Sponsor:
University of Kansas Medical Center
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Down Syndrome
Alzheimer Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The objectives of this study are to determine the feasibility and potential efficacy of remotely delivered group exercise sessions to increase daily moderate to vigorous physical activity in adults wi...
Detailed Description
This research study will compare 3 strategies for the delivery of an intervention to increase moderate to vigorous physical activity (MVPA) in community dwelling adults with Down Syndrome; remotely de...
Eligibility Criteria
Inclusion
- age 18 and over.
- Diagnosis of DS as determined by a Community Service Provider operating in our recruitment area under the auspices of a Community Developmental Disability Organization (CDDO).
- Sufficient functional ability to understand directions, communicate preferences, wants and needs through spoken language.
- Living at home with a parent/guardian or in a supported living environment with a caregiver who agrees to serve as a study partner.
- No plans to relocate outside the study area over the next 12 mos.
- Internet access in the home.
Exclusion
- Diagnosis of dementia as determine by the Cambridge Examination for Mental Disorders of Older People with Down Syndrome and others with intellectual disabilities.
- Unable to participate in MVPA.
- Pregnancy during the previous 6 mos., currently lactating or planned pregnancy in the following 12 mos.
- Serious medical risk, e.g., cancer, recent heart attack, stroke, angioplasty as determined by the PCP.
- Unwilling to be randomized.
- Participation in a regular exercise program, i.e. greater than or equal to 20 min/d greater than or equal to 3 d/wk.
- Contraindications for MRI, including metal implants or devices incompatible with MRI such as pacemakers, claustrophobia, and inability to lay in a supine position.
Key Trial Info
Start Date :
January 21 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 22 2023
Estimated Enrollment :
81 Patients enrolled
Trial Details
Trial ID
NCT04048759
Start Date
January 21 2020
End Date
November 22 2023
Last Update
July 23 2024
Active Locations (1)
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1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160